Synthesis of Triptorelin Lactate Catalyzed by Lipase in Organic Media
نویسندگان
چکیده
Triptorelin lactate was successfully synthesized by porcine pancreatic lipase (PPL) in organic solvents. The effects of acyl donor, substrate ratio, organic solvent, temperature, and water activity were investigated. Under the optimum conditions, a yield of 30% for its ester could be achieved in the reaction for about 48 h.
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2012